S.T. is a domesticated crow. He is a bird of simple pleasures: hanging out with his owner Big Jim, trading insults with Seattle's wild crows (those idiots) and enjoying the finest food humankind has to offer: Cheetos.
But when Big Jim's eyeball falls out of his head, S.T. starts to feel like something isn't right. His most tried-and-true remedies - from beak-delivered beer to the slobbering affection of the loyal, but dim-witted, dog Dennis - fail to cure his owner.
S.T. is left with no choice but to venture out into a frightening new world, where he discovers that the neighbours are devouring each other, and the local wildlife is abuzz with rumours of dangerous new predators roaming Seattle...
Humanity's extinction has arrived, and the only one determined to save it is a foul-mouthed crow.